Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 11/20 | 0.75 |
| ▸ | LIG1 | P18858 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | THRA | P10827 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12866351 | 1.00 | PCNA (0.75) | PCNALIG1THRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10802822 | 0.99 | PCNA (0.73) | PCNALIG1THRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10802814 | 0.99 | PCNA (0.73) | PCNALIG1THRBMEN1KMT2A | |
| SCHEMBL10878712 | 0.89 | PCNA (0.77) | PCNALIG1THRBMEN1KMT2A | |
| SCHEMBL3226219 | 0.88 | THRB (0.76) | PCNATHRBMEN1KMT2ALMNA | |
| SCHEMBL12866345 | 0.88 | THRB (0.76) | PCNATHRBMEN1KMT2ALMNA | |
| SCHEMBL8369339 | 0.87 | THRB (0.76) | PCNATHRBMEN1KMT2ALMNA | |
| SCHEMBL8369341 | 0.87 | THRB (0.76) | PCNATHRBMEN1KMT2ALMNA | |
| SCHEMBL12584317 | 0.86 | PCNA (0.64) | PCNALIG1THRBLMNATHRA | |
| Hydrochloric Acid SCHEMBL8825443 | 0.86 | THRB (0.74) | PCNATHRBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6458337-B1 | Diagnostic imaging contrast agent with improved in serum relaxivity | DIBRA S.P.A (IT) | 2002-10-01 | — | — | US | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |