Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.76 |
| ▸ | THRA | P10827 | 7/20 | 0.76 |
| ▸ | LMNA | P02545 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | PCNA | P12004 | 6/20 | 0.76 |
| ▸ | PPARG | P37231 | 3/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.76 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.76 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.76 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | GABRP | O00591 | 1/20 | 0.76 |
| ▸ | GABRD | O14764 | 1/20 | 0.76 |
| ▸ | F2 | P00734 | 1/20 | 0.76 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.76 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.76 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226219 | 1.00 | THRB (0.76) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL7903283 | 0.89 | THRB (0.74) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL25773008 | 0.89 | THRB (0.81) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL16124483 | 0.89 | THRB (0.81) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL12866351 | 0.88 | PCNA (0.75) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL12866377 | 0.88 | THRB (0.58) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL7599255 | 0.88 | PCNA (0.75) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL8369339 | 0.88 | THRB (0.76) | THRBTHRALMNAMEN1KMT2A | |
| SCHEMBL8369341 | 0.88 | THRB (0.76) | THRBTHRALMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10802822 | 0.87 | PCNA (0.73) | THRBTHRALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028554-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIIODOTHYRONINE AND THEIR THERAPEUTIC USE | UNIVERSITE JOSEPH FOURIER (FR) | 2011-02-03 | — | — | US | disclosed |
| US-20100075435-A1 | BIOTINYLATED THYROXINE | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075435-A1 | BIOTINYLATED THYROXINE | TPO, TSHR, THRB | THRB 3/4885THRA 4/4885LMNA 247/4885 |
| US-20110028554-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIIODOTHYRONINE AND THEIR THERAPEUTIC USE | TPO, HSD3B2, THRB | THRB 3/4885THRA 6/4885LMNA 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.