Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 14/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760648 | 0.94 | EPHX1 (0.40) | EPHX1ACHEFAAHCA12CA1 | |
| SCHEMBL21596988 | 0.92 | EPHX1 (0.43) | EPHX1ACHEFAAHCA12CA1 | |
| SCHEMBL25362201 | 0.92 | EPHX1 (0.43) | EPHX1ACHEFAAHCA12CA1 | |
| SCHEMBL759990 | 0.88 | ACHE (0.32) | EPHX1ACHE | |
| SCHEMBL7769422 | 0.82 | EPHX1 (0.33) | EPHX1ACHEFAAH | |
| SCHEMBL7769425 | 0.82 | EPHX1 (0.33) | EPHX1ACHEFAAHRAB9A | |
| SCHEMBL17393935 | 0.82 | ACHE (0.44) | EPHX1ACHE | |
| SCHEMBL11100479 | 0.82 | EPHX1 (0.52) | EPHX1ACHERAB9A | |
| SCHEMBL25345009 | 0.81 | ACHE (0.32) | ACHE | |
| SCHEMBL21059108 | 0.80 | EPHX1 (0.60) | EPHX1ACHEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658941-A | Near infrared fluorescent probe based on basic dye double-enzyme activation and preparation and application thereof | 山西大学 | 2024-03-08 | — | — | CN | claimed |
| CN-107602417-A | It is a kind of based on aggregation-induced emission mechanism can quick detection zinc ion fluorescence probe and preparation method and application | 华南理工大学 | 2018-01-19 | — | — | CN | claimed |
| CN-118239928-A | Fibroblast activation protein affinity compound and radioactive marker thereof | 南京思锘新药研发有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117769443-A | Fibroblast activation protein inhibitor and use thereof | 3B制药有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117658941-A | Near infrared fluorescent probe based on basic dye double-enzyme activation and preparation and application thereof | 山西大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-114907197-B | Preparation method of biaziridine-based photocrosslinking probe intermediate and derivative | 中国人民解放军海军军医大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-116368131-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116253724-A | Novel Smad3 protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-107207473-B | Compounds having muscarinic receptor antagonist and β 2 adrenergic receptor agonist activity | 奇斯药制品公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-110167933-A | Azole amides and amines as α V integrin inhibitors | 百时美施贵宝公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-108778273-A | bicyclic aryl monocyclic β -lactam compounds and methods of use thereof for treating bacterial infections | 默沙东公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-1993362-B | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL | 2010-12-15 | — | — | CN | disclosed |
| CN-1764650-B | 2, 3, 6-trisubstituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP | 2010-06-16 | — | — | CN | disclosed |
| CN-101525339-A | Novel oxabispidine compounds and their use in the treatment of cardiac arrhythmias | ASTRAZENECA AB | 2009-09-09 | — | — | CN | disclosed |
| CN-101243093-A | New oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |
| CN-101163675-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO KK (JP) | 2008-04-16 | — | — | CN | disclosed |
| CN-1993362-A | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL (JP) | 2007-07-04 | — | — | CN | disclosed |
| CN-1968956-A | Novel oxabispidine compounds and their use in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2007-05-23 | — | — | CN | disclosed |
| CN-1764650-A | 2, 3, 6-trisubstituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1735595-A | Substituted alkyl amido piperidines | LUNDBECK & CO AS H (DK) | 2006-02-15 | — | — | CN | disclosed |