Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773645 | 0.84 | ALDH1A1 (0.48) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7769422 | 0.83 | EPHX1 (0.33) | EPHX1ACHEFAAH | |
| SCHEMBL759928 | 0.82 | EPHX1 (0.37) | EPHX1ACHERAB9AFAAH | |
| SCHEMBL7771364 | 0.81 | EPHX1 (0.36) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7771474 | 0.80 | SMN1; SMN2 (0.42) | EPHX1ACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL760648 | 0.77 | EPHX1 (0.40) | EPHX1ACHEFAAH | |
| SCHEMBL7773594 | 0.76 | ALOX15 (0.44) | NPC1ALDH1A1 | |
| SCHEMBL25362201 | 0.75 | EPHX1 (0.43) | EPHX1ACHEFAAH | |
| SCHEMBL21596988 | 0.75 | EPHX1 (0.43) | EPHX1ACHEFAAH | |
| SCHEMBL7765955 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |