Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28182640 | 0.98 | LOXL2 (0.56) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL7747842 | 0.90 | LOXL2 (0.60) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL2333461 | 0.88 | LOXL2 (0.62) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL2331919 | 0.88 | LOXL2 (0.62) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL15155439 | 0.87 | CYP19A1 (0.53) | LOXL2CYP3A4HIF1AKDM4EALDH1A1 | |
| SCHEMBL336172 | 0.83 | LOXL2 (0.67) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL453732 | 0.83 | LOXL2 (0.56) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL7358307 | 0.83 | LOXL2 (0.56) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL4870247 | 0.83 | LOXL2 (0.56) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL2237676 | 0.83 | LOXL2 (0.56) | LOXL2NCF1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693198-B | 3 (1,2,4 triazoles simultaneously [4,3 a] 3 base of pyridine) 4 (3 base of 1H indoles) maleimide analog derivative and its preparation method and application | 浙江工业大学 | 2017-03-08 | — | — | CN | claimed |
| CN-104513252-B | Substituted urea derivative and its application in medicine | 广东东阳光药业有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-1178951-C | Noval erythromycin derivative, method for preparing and use thereof as drugs | ���˹��ء���³�� | 2004-12-08 | — | — | CN | disclosed |
| EP-0931088-B1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS DRUGS | AVENTIS PHARMA SA (FR) | 2002-10-09 | — | — | EP | disclosed |
| US-6162793-A | Erythromycin derivatives, method for preparing same and use thereof as drugs | HOECHST MARION ROUSSEL (FR) | 2000-12-19 | — | — | US | disclosed |
| CN-1226252-A | Noval erythromycin derivative, method for preparing and use thereof as drugs | HERST MARIEN RUSO COMPANY (FR) | 1999-08-18 | — | — | CN | disclosed |
| EP-0931088-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS DRUGS | HOECHST MARION ROUSSEL (FR) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998003530-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS DRUGS | HOECHST MARION ROUSSEL (FR) | 1998-01-29 | — | — | WO | disclosed |