Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107181 | 0.87 | SMN1; SMN2 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5127966 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1LMNAABCB1 | |
| SCHEMBL19007840 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL5127967 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1LMNAABCB1 | |
| SCHEMBL19007841 | 0.79 | NPC1 (0.47) | NPC1RAB9AALDH1A1CTSLCTSB | |
| SCHEMBL8363864 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15184648 | 0.78 | ALDH1A1 (0.53) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5097623 | 0.78 | LMNA (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5100754 | 0.77 | LMNA (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6254655 | 0.77 | LMNA (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983232-B1 | GUANIDINYLATION REAGENTS | UNIV CALIFORNIA (US) | 2002-11-13 | — | — | EP | claimed |