Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693650 | 0.91 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DMRGPRX4 | |
| SCHEMBL7523289 | 0.88 | THRA (0.43) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL7602501 | 0.86 | THRA (0.46) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL7519964 | 0.82 | KRAS (0.47) | HTR1AMAPTTDP1 | |
| SCHEMBL8465351 | 0.81 | PDE4D (0.47) | PDE4APDE4BPDE4CPDE4DHTR1A | |
| SCHEMBL7626410 | 0.80 | KMT2A (0.43) | FFAR4TNFRSF1AMAPT | |
| SCHEMBL7597538 | 0.80 | KRAS (0.46) | PDE4APDE4BPDE4CPDE4DTNFRSF1A | |
| SCHEMBL7517816 | 0.79 | ADCYAP1R1 (0.46) | PDE4APDE4BPDE4CPDE4DHTR1A | |
| SCHEMBL7044465 | 0.78 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DTHRA | |
| SCHEMBL7521268 | 0.78 | ATM (0.43) | PDE4APDE4BPDE4CPDE4DMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |