Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599536 | 0.86 | PDE4A (0.45) | THRATHRBFFAR4PDE4APDE4B | |
| SCHEMBL7601914 | 0.85 | MAPT (0.49) | MAPTNPSR1MEN1LMNACYP1A2 | |
| SCHEMBL7044465 | 0.85 | PDE4A (0.47) | THRATHRBPDE4APDE4BPDE4C | |
| SCHEMBL7523289 | 0.84 | THRA (0.43) | THRATHRBFFAR4PDE4APDE4B | |
| SCHEMBL7600520 | 0.84 | MAPT (0.50) | THRATHRBFFAR4MAPTNPSR1 | |
| Metrafenone SCHEMBL20788 | 0.82 | ALDH1A1 (0.42) | MAPTNPSR1MEN1LMNACYP1A2 | |
| Metrafenone SCHEMBL30013482 | 0.82 | ALDH1A1 (0.42) | MAPTNPSR1MEN1LMNACYP1A2 | |
| Metrafenone SCHEMBL29408434 | 0.82 | ALDH1A1 (0.42) | MAPTNPSR1MEN1LMNACYP1A2 | |
| SCHEMBL7599649 | 0.82 | APP (0.41) | THRBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7603075 | 0.81 | MAPT (0.46) | THRBMAPTNPSR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |