Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.46 |
| ▸ | MAP3K6 | O95382 | 2/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825764 | 1.00 | FDPS (0.54) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL5380631 | 0.86 | FDPS (0.51) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL5874038 | 0.85 | ADORA3 (0.62) | FDPSRAB9ACNR2ADORA3NPC1 | |
| SCHEMBL4411955 | 0.84 | FDPS (0.53) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL10051128 | 0.84 | FDPS (0.53) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL2361181 | 0.84 | KDM4E (0.56) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL13685315 | 0.81 | TRPV1 (0.49) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL4410540 | 0.80 | KMT2A (0.50) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL7937683 | 0.80 | FDPS (0.49) | FDPSDRD2DRD4DRD3RAB9A | |
| SCHEMBL31606592 | 0.80 | KMT2A (0.50) | FDPSDRD2DRD4DRD3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257976-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2016-12-28 | — | — | CN | disclosed |
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5411967-A | Antiinflammatory, immunosuppressant, antitumor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| CN-1091135-A | The carbamate of Wyeth-Ayerst Laboratories | AMERICAN HOME PROD (US) | 1994-08-24 | — | — | CN | disclosed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |