SCHEMBL759978

SCHEMBL759978

CC(C)(C)C1CC(C#N)CCN1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.33
DPP8 Q6V1X1 2/20 0.33
DPP9 Q86TI2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3563797 0.78 KDM2B (0.33) DPP4
SCHEMBL20702359 0.77 RIPK1 (0.37) DPP4
SCHEMBL28524745 0.76 RIPK1 (0.33) DPP4
SCHEMBL75974 0.76 RIPK1 (0.33) DPP4
SCHEMBL25348697 0.75 RIPK1 (0.32) DPP4
SCHEMBL1048496 0.75 DPP4 (0.35) DPP4
SCHEMBL18046082 0.75 ACE (0.33) DPP4
SCHEMBL5228762 0.75 RIPK1 (0.32) DPP4
SCHEMBL5078432 0.75 LMNA (0.41) DPP4
SCHEMBL4869792 0.75 RIPK1 (0.32) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175928-A1 MC2R MODULATOR COMPOUNDS Omass Therapeutics Limited (GB) 2024-08-29 WO disclosed
CN-116964048-A Bicyclic tetrahydroazepine derivatives for the treatment of cancer 豪夫迈·罗氏有限公司 2023-10-27 CN disclosed
EP-1942733-B1 RADIOLABELED GLYCINE TRANSPORTER INHIBITORS MERCK SHARP & DOHME (US) 2012-03-21 EP disclosed