Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339347 | 0.95 | PARP1 (0.63) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL221618 | 0.85 | PARP1 (0.53) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL29372946 | 0.85 | PARP1 (0.53) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL4113021 | 0.83 | PARP1 (0.56) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL28012033 | 0.83 | PARP1 (0.52) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL21450709 | 0.79 | PARP1 (0.63) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL28244498 | 0.77 | PARP1 (0.95) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL29089233 | 0.77 | PARP1 (0.66) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL7936537 | 0.77 | RAD52 (0.44) | PARP1MEN1KMT2ANPSR1USP2 | |
| SCHEMBL6848270 | 0.76 | PARP1 (0.63) | PARP1MEN1KMT2ANPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020025940-A1 | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and use for cellular assays in drug discovery | AURORA BIOSCIENCES CORPORATION | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020025940-A1 | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and use for cellular assays in drug discovery | PHAX, POLRMT, POLI | PARP1 662/4885MEN1 3890/4885KMT2A 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.