Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 4/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.74 |
| ▸ | ESR1 | P03372 | 14/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599292 | 1.00 | EBP (0.74) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL7801089 | 0.90 | ESR1 (0.67) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL7596148 | 0.88 | ESR1 (0.76) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL7596978 | 0.88 | ESR1 (0.76) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL13461620 | 0.88 | ESR1 (0.76) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL17164687 | 0.85 | ESR1 (0.79) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL17164682 | 0.85 | ESR1 (0.79) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL7602293 | 0.84 | ESR1 (0.65) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL10680278 | 0.82 | CYP2D6 (0.63) | EBPSIGMAR1ESR1ESR2CYP2D6 | |
| SCHEMBL13305614 | 0.81 | ESR1 (0.66) | EBPSIGMAR1ESR1ESR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161007-A1 | Non-steroidal modulators of estrogen receptors | PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2002-10-31 | — | — | US | claimed |
| US-20020161007-A1 | Non-steroidal modulators of estrogen receptors | PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161007-A1 | Non-steroidal modulators of estrogen receptors | ESRRB, ESR2, ESRRG | EBP 70/4885SIGMAR1 348/4885ESR1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.