Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599844 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7598059 | 0.84 | MTNR1A (0.47) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL26862817 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL17335643 | 0.80 | MTNR1A (0.81) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL8391662 | 0.79 | DRD2 (0.55) | MTNR1AMTNR1BROCK2MALT1HTR7 | |
| SCHEMBL8391659 | 0.79 | DRD2 (0.55) | MTNR1AMTNR1BROCK2MALT1HTR7 | |
| SCHEMBL8391660 | 0.79 | DRD2 (0.55) | MTNR1AMTNR1BROCK2MALT1HTR7 | |
| SCHEMBL8390675 | 0.79 | DRD2 (0.60) | HTR7 | |
| SCHEMBL8390678 | 0.79 | DRD2 (0.60) | HTR7 | |
| SCHEMBL8390680 | 0.79 | DRD2 (0.60) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781280-B1 | DERIVATIVES OF BENZOPYRAN AND OF BENZOTHIOPYRAN, THEIR PREPARATION AND THEIR USE AS AGONISTS OF DOPAMINERGIC RECEPTORS | ZAMBON SPA (IT) | 2002-11-06 | — | — | EP | disclosed |
| EP-0781280-A1 | DERIVATIVES OF BENZOPYRAN AND OF BENZOTHIOPYRAN, THEIR PREPARATION AND THEIR USE AS AGONISTS OF DOPAMINERGIC RECEPTORS | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008489-A1 | DERIVATIVES OF BENZOPYRAN AND OF BENZOTHIOPYRAN, THEIR PREPARATION AND THEIR USE AS AGONISTS OF DOPAMINERGIC RECEPTORS | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |