Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111571 | 0.85 | KMT2A (0.56) | FFAR1FFAR4KMT2ALMNAPDCD1 | |
| SCHEMBL3738754 | 0.84 | FFAR1 (0.53) | FFAR1FFAR4KMT2AL3MBTL1LMNA | |
| SCHEMBL5045725 | 0.84 | FFAR1 (0.47) | FFAR1FFAR4KMT2AMCL1BAD | |
| SCHEMBL28888278 | 0.84 | ABCC4 (0.44) | FFAR1FFAR4KMT2ALMNACYP2C19 | |
| SCHEMBL29636261 | 0.84 | ABCC4 (0.44) | FFAR1FFAR4KMT2ALMNACYP2C19 | |
| SCHEMBL7598404 | 0.84 | CYP2C19 (0.54) | FFAR1FFAR4KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL7410920 | 0.82 | KMT2A (0.53) | FFAR1FFAR4KMT2ALMNAPDCD1 | |
| SCHEMBL7596724 | 0.82 | FFAR1 (0.52) | FFAR1FFAR4KMT2AL3MBTL1TDP1 | |
| SCHEMBL6598295 | 0.79 | KCNA5 (0.44) | KMT2ACYP2C19MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL812762 | 0.77 | PDCD1 (0.57) | FFAR1FFAR4KMT2APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| US-6127414-A | NPY antagonists | ASTRA AKTIEBOLAG (SE) | 2000-10-03 | — | — | US | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |