SCHEMBL29636261

SCHEMBL29636261

O=C(Cl)Cc1ccc(-c2ccccc2CC(=O)Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.43
PTGER1 P34995 2/20 0.42
PTGER4 P35408 2/20 0.42
PTGER3 P43115 2/20 0.42
PTGER2 P43116 2/20 0.42
FFAR1 O14842 9/20 0.41
FFAR4 Q5NUL3 9/20 0.41
LTB4R2 Q9NPC1 2/20 0.40
CYP2C19 P33261 1/20 0.40
FOLH1 Q04609 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28888278 1.00 ABCC4 (0.44) ABCC4LMNAGAATSHRPTGS1
SCHEMBL3111571 0.87 KMT2A (0.56) LMNAPTGS1KMT2APTGER1PTGER4
SCHEMBL7598404 0.86 CYP2C19 (0.54) PTGS1KMT2AFFAR1FFAR4CYP2C19
SCHEMBL7600170 0.84 FFAR1 (0.46) LMNAGAAPTGS1KMT2AFFAR1
SCHEMBL7410920 0.84 KMT2A (0.53) LMNAPTGS1KMT2APTGER1PTGER4
SCHEMBL6598295 0.81 KCNA5 (0.44) HTTKMT2ACYP2C19FOLH1
SCHEMBL7596724 0.80 FFAR1 (0.52) GAAKMT2AFFAR1FFAR4
SCHEMBL28408449 0.80 PTGS1 (0.66) ABCC4LMNAGAATSHRPTGS1
SCHEMBL29191992 0.79 FOLH1 (0.44) ABCC4LMNAGAATSHRPTGS1
SCHEMBL2898411 0.79 LMNA (0.69) ABCC4LMNAGAATSHRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117393718-A SiO (silicon dioxide) x Base composite anode material, pole piece and preparation method 南昌大学 2024-01-12 CN claimed
CN-117181020-A Method for preparing nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2023-12-08 CN claimed
CN-117393718-A SiO (silicon dioxide) x Base composite anode material, pole piece and preparation method 南昌大学 2024-01-12 CN disclosed
CN-117181020-A Method for preparing nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2023-12-08 CN disclosed
CN-111592758-B Polyimide film with low thermal expansion coefficient and preparation method thereof 浙江中科玖源新材料有限公司 2022-05-20 CN disclosed
CN-111111475-B Preparation method of graphene oxide modified triptycenyl polyamide separation membrane 南京工业大学 2022-03-22 CN disclosed