Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | DRD4 | P21917 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949312 | 0.96 | DRD2 (0.57) | DPP7DRD2DRD4ALDH1A1LTA4H | |
| SCHEMBL16007156 | 0.96 | DRD2 (0.57) | DPP7DRD2DRD4ALDH1A1LTA4H | |
| SCHEMBL7393471 | 0.91 | DRD4 (0.67) | DPP7DRD2DRD4LTA4HMCHR1 | |
| SCHEMBL1781392 | 0.91 | DRD4 (0.67) | DPP7DRD2DRD4LTA4HMCHR1 | |
| SCHEMBL7500995 | 0.91 | DRD4 (0.67) | DPP7DRD2DRD4LTA4HMCHR1 | |
| SCHEMBL7374896 | 0.88 | DRD2 (0.55) | DPP7DRD2DRD4ALDH1A1LTA4H | |
| SCHEMBL5143427 | 0.85 | ALDH1A1 (0.60) | DPP7DRD2DRD4ALDH1A1DRD3 | |
| SCHEMBL1623588 | 0.85 | ALDH1A1 (0.60) | DPP7DRD2DRD4ALDH1A1DRD3 | |
| SCHEMBL12655772 | 0.84 | S1PR1 (0.53) | DPP7DRD2DRD4LTA4HMCHR1 | |
| SCHEMBL555720 | 0.83 | KMT2A (0.62) | DPP7DRD2DRD4ALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057223-A2 | COMPOUNDS AZEPANE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | claimed |
| EP-3356345-B1 | HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS | MAX PLANCK GESELLSCHAFT (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-1137412-A4 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1137412-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000033788-A2 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | AMERICAN BIOGENETIC SCIENCES INC. (US) | 2000-06-15 | — | — | WO | disclosed |