Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7595781 | 0.99 | SIRT2 (0.43) | SIRT2CTSLSIRT5CPB1CPB2 | |
| Hydrochloric Acid SCHEMBL7596809 | 0.88 | SIRT2 (0.48) | SIRT2CPB1CPB2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL7600885 | 0.88 | SIRT2 (0.48) | SIRT2CPB1CPB2MMP2MMP9 | |
| SCHEMBL8068262 | 0.85 | SIRT2 (0.43) | SIRT2CTSLSIRT5MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL7597311 | 0.84 | MMP2 (0.52) | SIRT2CPB1CPB2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL8072552 | 0.84 | SIRT2 (0.42) | SIRT2CTSLSIRT5MMP2MMP9 | |
| SCHEMBL7600478 | 0.81 | FOLH1 (0.38) | SIRT2CTSLFOLH1NPY1RNPY5R | |
| SCHEMBL7597915 | 0.81 | FOLH1 (0.38) | SIRT2CTSLFOLH1NPY1RNPY5R | |
| Hydrochloric Acid SCHEMBL7596698 | 0.81 | MMP2 (0.52) | SIRT2CPB1CPB2MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL7595151 | 0.81 | MMP2 (0.52) | SIRT2CPB1CPB2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |