⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442174 | 0.85 | — | — | |
| SCHEMBL30723488 | 0.84 | TSHR (0.32) | — | |
| SCHEMBL8232153 | 0.80 | TSHR (0.42) | — | |
| SCHEMBL4244087 | 0.76 | CES1 (0.47) | — | |
| SCHEMBL7591423 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL2638345 | 0.73 | CES1 (0.45) | — | |
| SCHEMBL8827997 | 0.73 | TSHR (0.48) | — | |
| SCHEMBL25632800 | 0.73 | CES2 (0.32) | — | |
| SCHEMBL10535995 | 0.73 | — | — | |
| SCHEMBL60363 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663394-B1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL CO (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-5498725-A | Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0663394-A1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |