SCHEMBL760059

SCHEMBL760059

COc1ccc(C(c2ccc(Oc3ccc(C(=O)c4ccc(C)cc4)cc3)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
MAPK1 P28482 2/20 0.52
RAB9A P51151 2/20 0.48
NPC1 O15118 2/20 0.48
MMP13 P45452 3/20 0.48
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
PARP10 Q53GL7 1/20 0.46
HPGD P15428 1/20 0.46
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341728 1.00 MAPT (0.52) MAPTMAPK1RAB9ANPC1MMP13
SCHEMBL15760404 1.00 MAPT (0.52) MAPTMAPK1RAB9ANPC1MMP13
SCHEMBL13910617 0.96 MAPT (0.49) MAPTMAPK1RAB9ANPC1MMP13
SCHEMBL758563 0.94 MMP13 (0.53) MAPTMAPK1RAB9AMMP13LMNA
SCHEMBL14511013 0.94 MMP13 (0.53) MAPTMAPK1RAB9AMMP13LMNA
SCHEMBL16378711 0.94 MAPT (0.51) MAPTMAPK1RAB9ALMNAMEN1
SCHEMBL14599493 0.94 MMP13 (0.53) MAPTMAPK1RAB9AMMP13LMNA
SCHEMBL12242064 0.93 MAPT (0.49) MAPTMAPK1RAB9ANPC1MMP13
SCHEMBL26671385 0.93 MAPT (0.49) MAPTMAPK1RAB9ANPC1MMP13
SCHEMBL13272459 0.89 ESR1 (0.50) MAPTMAPK1MMP13LMNAPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20170253764-A1 FILM-FORMING COMPOSITION INCLUDING THERMOSETTING RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-09-07 US disclosed
US-9505962-B2 Adhesive composition containing resin having carbon-carbon multiple bond NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-11-29 US disclosed
US-20160311979-A1 COMPOSITION FOR FORMING PASSIVATION FILM, INCLUDING RESIN HAVING CARBON-CARBON MULTIPLE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-27 US disclosed
US-20160158692-A1 RESIN COMPOSITION AND CARBON DIOXIDE GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-09 US disclosed
US-20160158692-A1 RESIN COMPOSITION AND CARBON DIOXIDE GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-09 US disclosed
US-20140374887-A1 COMPOSITION FOR FORMING PASSIVATION FILM, INCLUDING RESIN HAVING CARBON-CARBON MULTIPLE BOND NISSAN CHEMICAL IMDUSTRIES, LTD. (JP) 2014-12-25 US disclosed
US-20130177763-A1 ADHESIVE COMPOSITION CONTAINING RESIN HAVING CARBON-CARBON MULTIPLE BOND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-07-11 US disclosed
US-20130052564-A1 POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY, AND SOLID POLYMER FUEL CELL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-28 US disclosed
US-20080241628-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO. LTD. (JP) 2008-10-02 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
US-20070231671-A1 Catalyst Material For Use In Fuel Cell, Catalyst Membrane, Membrane Electrode Assembly and Fuel Cell FUJIFILM CORPORATION 2007-10-04 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-20070166591-A1 POLYMER ELECTROLYTE COMPOSITION AND APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-19 US disclosed
US-20070112169-A1 Sulfonated polyaryletherketones GENERAL ELECTRIC COMPANY 2007-05-17 US disclosed
US-20070112169-A1 Sulfonated polyaryletherketones GENERAL ELECTRIC COMPANY 2007-05-17 US disclosed
US-20070066759-A1 Block copolymers and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-20070004900-A1 Triblock copolymers with acidic groups GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2007-01-04 US disclosed