SCHEMBL758563

SCHEMBL758563

Cc1ccc(C(=O)c2ccc(Oc3ccc(C(c4ccc(Oc5ccc(C(=O)c6ccc(C)cc6)cc5)cc4)(C(F)(F)F)C(F)(F)F)cc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 4/20 0.53
LMNA P02545 2/20 0.50
ALDH1A1 P00352 1/20 0.50
SRD5A2 P31213 3/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 1/20 0.44
CA2 P00918 1/20 0.44
MAPK14 Q16539 2/20 0.43
HPGD P15428 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TSHR P16473 1/20 0.42
MMP2 P08253 1/20 0.42
CYP3A4 P08684 1/20 0.42
STAT3 P40763 1/20 0.42
RAB9A P51151 1/20 0.42
ELANE P08246 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511013 1.00 MMP13 (0.53) MMP13LMNAALDH1A1SRD5A2MAPT
SCHEMBL14599493 1.00 MMP13 (0.53) MMP13LMNAALDH1A1SRD5A2MAPT
SCHEMBL13749963 0.94 MMP13 (0.48) MMP13LMNAALDH1A1SRD5A2MAPT
SCHEMBL13917643 0.94 SRD5A2 (0.50) MMP13LMNAALDH1A1SRD5A2MAPK14
SCHEMBL12242110 0.94 ESR1 (0.50) MMP13LMNAALDH1A1SRD5A2MAPT
SCHEMBL13272459 0.94 ESR1 (0.50) MMP13LMNAALDH1A1SRD5A2MAPT
SCHEMBL760059 0.94 MAPT (0.52) MMP13LMNAALDH1A1MAPTMAPK1
SCHEMBL12341728 0.94 MAPT (0.52) MMP13LMNAALDH1A1MAPTMAPK1
SCHEMBL15760404 0.94 MAPT (0.52) MMP13LMNAALDH1A1MAPTMAPK1
SCHEMBL2696709 0.93 MAPT (0.49) MMP13LMNAALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20160158692-A1 RESIN COMPOSITION AND CARBON DIOXIDE GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-09 US disclosed
US-20140154610-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF JSR CORPORATION (JP) 2014-06-05 US disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
US-8236206-B2 Electrode catalyst layer JSR CORPORATION (JP) 2012-08-07 US disclosed
US-8236920-B2 Polyarylene and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-8211558-B2 Crosslinked polymer electrolyte and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US disclosed
US-20120164558-A1 BIPHENYLTETRASULFONIC ACID COMPOUND, METHOD FOR PRODUCING SAME, POLYMER AND POLYMER ELECTROLYTE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-28 US disclosed
US-8138231-B2 Polymer having oxycarbon group, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-20 US disclosed
US-7572535-B2 Polymer electrolyte membranes, catalyst coated membranes, and membrane electrolyte assemblies for use in fuel cells; environmentally friendly vehicles POLYFUEL, INC. (US) 2009-08-11 US disclosed
US-7544433-B2 Electrode structure for polymer electrolyte fuel cells, and polymer electrolyte fuel cell using the same HONDA MOTOR CO., LTD. (JP) 2009-06-09 US disclosed
US-20090110995-A1 POLYMER HAVING OXYCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20090099331-A1 SYNTHESIS AND CHARACTERIZATION OF A NOVEL PROTON EXCHANGE MEMBRANE (PEM) FOR APPLICATIONS IN FUEL CELLS STMICROELECTRONICS S.R.L. (IT) 2009-04-16 US disclosed
US-20090036632-A1 Polyarylene and Process for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-05 US disclosed
US-20080287646-A1 Polyarylene and Method for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2008-11-20 US disclosed
US-20080004360-A1 Polyarylene Polymer And Use Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-20070111071-A1 Proton conducting membrane JSR CORPORATION (JP) 2007-05-17 US disclosed
US-20070020500-A1 Membrane-electrode structure for solid polymer fuel cell and solid polymer fuel cell HONDA MOTOR CO., LTD 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164558-A1 BIPHENYLTETRASULFONIC ACID COMPOUND, METHOD FOR PRODUCING SAME, POLYMER AND POLYMER ELECTROLYTE ARSA, PDXK, AIPL1 MMP13 3938/4885LMNA 3614/4885ALDH1A1 755/4885
US-20090036632-A1 Polyarylene and Process for Producing the Same CYP1A1, CYP1B1, C1R MMP13 3396/4885LMNA 2226/4885ALDH1A1 1881/4885
US-20080287646-A1 Polyarylene and Method for Producing the Same CYP1A1, C1R, CBR1 MMP13 3167/4885LMNA 2889/4885ALDH1A1 602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.