Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524117 | 0.90 | KRAS (0.72) | KRASPTGS2HTR1AMAOAMAOB | |
| SCHEMBL9524111 | 0.90 | KRAS (0.72) | KRASPTGS2HTR1AMAOAMAOB | |
| SCHEMBL14318109 | 0.84 | KRAS (1.00) | KRASPTGS2MAOAMAOBMAPT | |
| SCHEMBL9478343 | 0.83 | MAOB (0.73) | KRASPTGS2MAOAMAOBMAPT | |
| SCHEMBL9478353 | 0.83 | MAOB (0.73) | KRASPTGS2MAOAMAOBMAPT | |
| SCHEMBL9523755 | 0.82 | PTGS2 (0.69) | KRASPTGS2MAOAMAOBMAPT | |
| SCHEMBL9523759 | 0.82 | PTGS2 (0.69) | KRASPTGS2MAOAMAOBMAPT | |
| SCHEMBL4258994 | 0.81 | PTGS2 (1.00) | KRASPTGS2MAPTALDH1A1LMNA | |
| SCHEMBL6309969 | 0.81 | PTGS2 (1.00) | KRASPTGS2MAPTALDH1A1LMNA | |
| SCHEMBL4258992 | 0.81 | PTGS2 (1.00) | KRASPTGS2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138165-B2 | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138165-B2 | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES, INC. (US) | 2012-03-20 | — | — | US | disclosed |