Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551636 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30593398 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL4103521 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL916064 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3021416 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL722159 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8003645 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2462921 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL19656190 | 0.95 | TLR8 (0.60) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29629266 | 0.90 | ALDH1A1 (0.53) | TLR8KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304536-A | Polyarylacridine anion exchange membrane with high ion conductivity and high dimensional stability, and preparation method and application thereof | 安徽大学 | 2023-12-29 | — | — | CN | claimed |
| CN-116283768-A | Preparation method of aryl acridine compound | 西安凯翔生物医药科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-114409703-A | Heat-excited delayed fluorescence aromatic phosphine oxide material of azacyclo-diphenyl sulfone and synthetic method and application thereof | 黑龙江大学 | 2022-04-29 | — | — | CN | claimed |
| CN-110698399-B | Preparation method of aryl acridine derivative synthesized by palladium catalysis | 温州大学 | 2021-06-08 | — | — | CN | claimed |
| CN-110698399-A | Aryl acridine derivative synthesized by palladium catalysis and preparation method thereof | 温州大学 | 2020-01-17 | — | — | CN | claimed |
| CN-118239888-A | Modularized synthesis method and application of acridine compound | 厦门大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-117597327-A | Pharmaceutical preparation | 第一波动生物制药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117567490-A | Organic boron fused ring compound containing 9, 9-aryl acridine and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2024-02-20 | — | — | CN | disclosed |
| CN-117304536-A | Polyarylacridine anion exchange membrane with high ion conductivity and high dimensional stability, and preparation method and application thereof | 安徽大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-117304536-A | Polyarylacridine anion exchange membrane with high ion conductivity and high dimensional stability, and preparation method and application thereof | 安徽大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-116283768-A | Preparation method of aryl acridine compound | 西安凯翔生物医药科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283768-A | Preparation method of aryl acridine compound | 西安凯翔生物医药科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-5663074-A | INCUBATION OF FOLATE WITH AMINE REACTIVE COMPOUND, ACTIVATION AND INCUBATION THE ACRIDINIUM ESTER-FOLATE CONJUGATE | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0778946-A1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN, INC. (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996007912-A1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN, INC. (US) | 1996-03-14 | — | — | WO | disclosed |
| EP-0263657-B1 | POLYSUBSTITUTED ARYL ACRIDINIUM ESTERS | Ciba Corning Diagnostics Corp. (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5110932-A | Chemiluminescent immunoassay | CIBA CORNING DIAGNOSTICS CORP. (US) | 1992-05-05 | — | — | US | disclosed |
| US-4918192-A | LUMINESCENCE; LABELS FOR IMMUNOASSAY | CIBA CORNING DIAGNOSTICS CORP. (US) | 1990-04-17 | — | — | US | disclosed |
| US-4745181-A | STABLE LABELS FOR CHEMILUMINESCENT IMMUNOASSAY | CIBA CORNING DIAGNOSTICS CORP. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0263657-A2 | Polysubstituted aryl acridinium esters | Ciba Corning Diagnostics Corp. (US) | 1988-04-13 | — | — | EP | disclosed |