Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551636 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL3021416 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL4103521 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL2462921 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL916064 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL722159 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL30593398 | 1.00 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL7600918 | 0.98 | TLR8 (0.61) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL19656190 | 0.94 | TLR8 (0.60) | TLR8KDM4EALDH1A1GLAGAA | |
| SCHEMBL28491074 | 0.92 | ALDH1A1 (0.53) | TLR8KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751951-A4 | DIAGNOSIS, THERAPY AND CELLULAR AND ANIMAL MODELS FOR DISEASES ASSOCIATED WITH MITOCHONDRIAL DEFECTS | MITOKOR (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0751951-A1 | DIAGNOSIS, THERAPY AND CELLULAR AND ANIMAL MODELS FOR DISEASES ASSOCIATED WITH MITOCHONDRIAL DEFECTS | Mitokor (US) | 1997-01-08 | — | — | EP | disclosed |