Stearic Acid

Stearic Acid

SCHEMBL7600941

C(OCC1CO1)C1CO1.CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
GPR84 Q9NQS5 7/20 0.57
PPARG P37231 7/20 0.57
PPARD Q03181 7/20 0.57
PPARA Q07869 7/20 0.57
HDAC11 Q96DB2 5/20 0.57
TSHR P16473 4/20 0.57
PTPN1 P18031 3/20 0.57
TLR2 O60603 2/20 0.57
FABP4 P15090 2/20 0.57
KMT2A Q03164 2/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
MEN1 O00255 1/20 0.57
ESR1 P03372 1/20 0.57
ALOX15 P16050 1/20 0.57
PDE4A P27815 1/20 0.57
PDE3A Q14432 1/20 0.57
HSD17B10 Q99714 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octanoic Acid SCHEMBL9233254 1.00 ALDH1A1 (0.59) ALDH1A1TDP1GPR84PPARGPPARD
Sebacic Acid SCHEMBL11139033 0.91 TSHR (0.48) ALDH1A1TDP1GPR84PPARGPPARD
Adipic Acid SCHEMBL475382 0.89 TSHR (0.50) ALDH1A1TDP1TSHRSLC22A6SMN1; SMN2
Stearic Acid SCHEMBL8863455 0.84 ALDH1A1 (0.56) ALDH1A1TDP1FABP3SMN1; SMN2
Heptane SCHEMBL7774936 0.84 ALDH1A1 (0.80) ALDH1A1TDP1TSHRSMN1; SMN2
Tridecane SCHEMBL2035596 0.84 ALDH1A1 (0.80) ALDH1A1TDP1TSHRSMN1; SMN2
Undecane SCHEMBL2029986 0.84 ALDH1A1 (0.80) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL7775059 0.84 ALDH1A1 (0.80) ALDH1A1TDP1TSHRSMN1; SMN2
Hexadecane SCHEMBL2069576 0.84 ALDH1A1 (0.80) ALDH1A1TDP1TSHRSMN1; SMN2
Pentadecane SCHEMBL7773050 0.84 ALDH1A1 (0.80) ALDH1A1TDP1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160177050-A1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE MADE OF THE THERMOPLASTIC RESIN COMPOSITION, AND METHOD OF PREPARING THE THERMOPLASTIC RESIN COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-23 US claimed
CN-116670176-A Process for producing denatured cellulose fiber cake 花王株式会社 2023-08-29 CN disclosed
CN-112088170-A Process for producing modified cellulose fiber and modified cellulose fiber 花王株式会社 2020-12-15 CN disclosed
CN-111511980-A Method for producing finely-divided hydrophobically modified cellulose fiber 花王株式会社 2020-08-07 CN disclosed
US-20160177050-A1 THERMOPLASTIC RESIN COMPOSITION, MOLDED ARTICLE MADE OF THE THERMOPLASTIC RESIN COMPOSITION, AND METHOD OF PREPARING THE THERMOPLASTIC RESIN COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-23 US disclosed
CN-102666634-B Aqueous epoxy resin dispersions CYTEC AUSTRIA GMBH 2015-03-25 CN disclosed
CN-102388079-B One-pack type cyanate-epoxy composite resin composition ADEKA CORP 2014-03-05 CN disclosed
CN-102666634-A Aqueous epoxy resin dispersions CYTEC AUSTRIA GMBH 2012-09-12 CN disclosed
CN-102388079-A One-pack type cyanate-epoxy composite resin composition ADEKA CORP 2012-03-21 CN disclosed
CN-1100794-C Thermoplastic biodegradable polysaccharide derivatives, process for the manufacture thereof and use thereof WOLFF WALSRODE AG (DE) 2003-02-05 CN disclosed
US-6362330-B1 FOR PRODUCING MOULDED ARTICLES, FIBRES, FILMS AND ALSO FOAMS OR COATINGS WOLFF WOLSRODE AG (DE) 2002-03-26 US disclosed
US-6071984-A TENSILE MOLDULUS OF ELASTICITY, TOUGHNESS, STRENGTH; COMPOSTABILITY; FOR MAKING INJECTION MOLDED ARTILCES AS FLOWER POTS, PLANT POTS, PLANT TIES, WREATH STIFFENERS, GRAVE-LIGHT SURROUNDS, COFFINS, COFFIN PARTS BAYER AKTIENGESELLSCHAFT (DE) 2000-06-06 US disclosed
US-5827905-A POLYESTERLACTAMS, AND REINFORCEMENT MATERIAL CHOSEN FROM WOOD FLOUR, GYPSUM, WOLLASTONITE, CHALK, KAOLIN, AND CELLULOSE BAYER AKTIENGESELLSCHAFT (DE) 1998-10-27 US disclosed
CN-1152007-A Biodegradable plastics filled with reinforcing materials BAYER AG (DE) 1997-06-18 CN disclosed
US-5639865-A Thermoplastic biodegradable polysaccharide derivatives, process for the manufacture thereof and use thereof WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) 1997-06-17 US disclosed
CN-1031758-C Lubricant for refrigeration compressors HITACHI LTD (JP) 1996-05-08 CN disclosed
CN-1114655-A Thermoplastic biodegradable polysaccharide derivatives, process for the manufacture thereof and use thereof WOLFF WALSRODE AG (DE) 1996-01-10 CN disclosed
US-5466794-A Thermoplastic cellulose ether ester graft copolymers and process for their production WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) 1995-11-14 US disclosed