Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590542 | 0.94 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTTSHRLMNATP53 | |
| Fluoride SCHEMBL7601046 | 0.92 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTTSHRLMNATP53 | |
| SCHEMBL7600826 | 0.82 | UBE2T (0.61) | SMN1; SMN2MAPTTSHRLMNANPC1 | |
| SCHEMBL7598313 | 0.82 | TP53 (0.70) | SMN1; SMN2MAPTLMNATP53NPC1 | |
| SCHEMBL11328744 | 0.80 | MAPT (0.48) | SMN1; SMN2MAPTTSHRLMNATP53 | |
| SCHEMBL12597396 | 0.79 | LIPG (0.59) | SMN1; SMN2MAPTTSHRLMNATP53 | |
| SCHEMBL3465479 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTTSHRLMNATP53 | |
| SCHEMBL226465 | 0.75 | UBE2T (0.70) | SMN1; SMN2MAPTTSHRLMNANPC1 | |
| SCHEMBL1420033 | 0.75 | TP53 (0.81) | SMN1; SMN2MAPTLMNATP53NPC1 | |
| Bromide SCHEMBL7601035 | 0.73 | UBE2T (0.68) | SMN1; SMN2MAPTTSHRLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747448-B1 | Rigidized monomethine cyanine dyes | UNIV CARNEGIE MELLON (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-0747448-A2 | Rigidized monomethine cyanine dyes | CARNEGIE-MELLON UNIVERSITY (US) | 1996-12-11 | — | — | EP | disclosed |