Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | PGK1 | P00558 | 3/20 | 0.44 |
| ▸ | PGK2 | P07205 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838984 | 1.00 | ADORA2A (0.53) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL6839736 | 0.90 | PGK1 (0.45) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL7205090 | 0.89 | ADORA2A (0.52) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL6839116 | 0.87 | ADORA2A (0.51) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL6839242 | 0.86 | PGK1 (0.52) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL7454631 | 0.85 | ADORA2A (0.53) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL6839781 | 0.84 | ADORA3 (0.53) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7603058 | 0.82 | ADORA2A (0.50) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL6838958 | 0.82 | ADORA2A (0.50) | ADORA2AADORA2BPGK1PGK2ADORA3 | |
| SCHEMBL6838929 | 0.82 | ADORA2A (0.50) | ADORA2AADORA2BPGK1PGK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051425-B1 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-30 | — | — | EP | claimed |