Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420138 | 0.89 | PLA2G7 (0.68) | PLA2G7CYP3A4 | |
| SCHEMBL4411608 | 0.82 | PLA2G7 (0.57) | PLA2G7CYP3A4 | |
| SCHEMBL4425737 | 0.81 | PLA2G7 (0.59) | PLA2G7CYP3A4 | |
| SCHEMBL4412340 | 0.79 | PLA2G7 (0.51) | PLA2G7CYP3A4 | |
| SCHEMBL4415976 | 0.78 | PLA2G7 (0.57) | PLA2G7CYP3A4 | |
| SCHEMBL4419222 | 0.76 | PLA2G7 (0.57) | PLA2G7 | |
| SCHEMBL4552007 | 0.75 | PLA2G7 (0.74) | PLA2G7CYP3A4 | |
| SCHEMBL4416174 | 0.75 | PLA2G7 (0.59) | PLA2G7 | |
| SCHEMBL4385379 | 0.74 | PLA2G7 (0.59) | PLA2G7CYP3A4 | |
| SCHEMBL3538336 | 0.73 | PLA2G7 (0.58) | PLA2G7CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175408-A1 | PYRIMIDINONE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066567-A1 | PYRIMIDINONE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-09 | — | — | WO | disclosed |