Thiosalicylic Acid

Thiosalicylic Acid

SCHEMBL7601204

COC(=O)c1ccccc1S.O=C(O)c1ccccc1S

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.70
HDAC8 Q9BY41 1/20 0.70
TSHR P16473 3/20 0.53
LMNA P02545 1/20 0.53
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CFTR P13569 1/20 0.52
KDM4E B2RXH2 3/20 0.51
HPGD P15428 1/20 0.51
ALOX15 P16050 2/20 0.50
POLB P06746 1/20 0.50
ATM Q13315 1/20 0.50
SLC6A3 Q01959 1/20 0.49
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
KMT2A Q03164 1/20 0.46
MYC P01106 1/20 0.45
TDP1 Q9NUW8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212175 0.92 TSHR (0.61) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL28267652 0.86 MAPT (0.86) MAPTHDAC8TSHRLMNAHSD17B10
Bicarbonate SCHEMBL28234213 0.85 TSHR (0.53) MAPTHDAC8TSHRLMNAHSD17B10
SCHEMBL927517 0.85 CA1 (0.54) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL28933918 0.84 MAPT (0.91) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL3073817 0.84 MAPT (0.91) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL31208541 0.84 MAPT (1.00) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL50376 0.84 MAPT (1.00) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL28313023 0.84 MAPT (1.00) MAPTHDAC8TSHRLMNAHSD17B10
Thiosalicylic Acid SCHEMBL629705 0.84 MAPT (1.00) MAPTHDAC8TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1259482-A2 SULFUR CONTAINING COMPOUNDS University Health Network (CA) 2002-11-27 EP disclosed
WO-2001062668-A2 SULFUR CONTAINING COMPOUNDS UNIVERSITY HEALTH NETWORK (CA) 2001-08-30 WO disclosed