SCHEMBL7601474

SCHEMBL7601474

CC1=C2c3c(C(C)C)cc(C(C)C)cc3C1[Hf](C)(C)C1C(C)=C(c3c(C(C)C)cc(C(C)C)cc31)[Si]2(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
FABP3 P05413 2/20 0.31
FABP4 P15090 2/20 0.31
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17386634 0.82 ANPEP (0.32) GABRA1GABRB2
SCHEMBL7599154 0.81 ROCK2 (0.30) GABRA1GABRB2
Hydrochloric Acid SCHEMBL4295268 0.79 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL797581 0.78
SCHEMBL7596492 0.77 HTR2A (0.33) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL7627230 0.75
SCHEMBL4622292 0.72
Hydrochloric Acid SCHEMBL3686918 0.72 GABRA1 (0.31) GABRA1GABRB2FABP3FABP4
SCHEMBL7602956 0.69
SCHEMBL7597048 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed