Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796856 | 0.86 | CNR2 (0.33) | HIF1ASMN1; SMN2ALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL8606718 | 0.80 | MAPT (0.34) | HIF1ASMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL7598157 | 0.72 | NPC1 (0.33) | ALDH1A1LMNARAB9ANPC1CYP2D6 | |
| SCHEMBL7627235 | 0.69 | MYB (0.35) | — | |
| SCHEMBL20101688 | 0.64 | CYP1A2 (0.57) | SMN1; SMN2ALDH1A1HTTTP53MEN1 | |
| SCHEMBL2698582 | 0.63 | MAPT (0.51) | SMN1; SMN2ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL29428421 | 0.63 | MAPT (0.51) | SMN1; SMN2ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL27409851 | 0.63 | CYP1A1 (0.42) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12989388 | 0.61 | CYP11B1 (0.52) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7699015 | 0.60 | MAPT (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| US-6255531-B1 | POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |