Isopropylbenzene

Isopropylbenzene

SCHEMBL7601546

CC(C)c1ccccc1.CO.OO

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 2/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
ADRA2A P08913 1/20 0.50
HIF1A Q16665 1/20 0.50
ALDH1A1 P00352 2/20 0.48
CYP2D6 P10635 3/20 0.46
CHRM2 P08172 1/20 0.46
ADRA1A P35348 1/20 0.46
RGS12 O14924 1/20 0.46
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
NFKB1 P19838 1/20 0.46
HTR2A P28223 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylbenzene SCHEMBL4087648 1.00 ADRA2C (0.50) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL30804544 0.97 ADRA2C (0.52) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL16627 0.97 ADRA2C (0.52) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL4795494 0.97 ADRA2C (0.52) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL18614726 0.97 ADRA2C (0.52) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL23421101 0.97 ADRA2C (0.52) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL6320513 0.97 ADRA2C (0.52) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL11051581 0.94 ADRA2C (0.50) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL28421110 0.94 ADRA2C (0.50) ADRA2CKDM4ELMNAADRA2AHIF1A
Isopropylbenzene SCHEMBL23501477 0.94 ALDH1A1 (0.54) ADRA2CKDM4ELMNAADRA2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436360-B1 METHANOL, CUMENE HYDROPEROXIDE, AND CUMENE BYPRODUCTS IN THE MANUFACTURE OF PHENOL; AVOIDING CATALYST DEACTIVATION BY PHENOL TAR FORMATION; GAS FLOW THROUGH ROASTED OXIDE GUARD BED AND THEN THROUGH A PALLADIUM OXIDATION CATALYST GENERAL ELECTRIC COMPANY 2002-08-20 US claimed
CN-111100229-B Polyvinyl alcohol and preparation method thereof 中国石油化工股份有限公司 2022-09-13 CN disclosed