Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597929 | 1.00 | CA1 (0.45) | CA1CA2ACHEFOLH1ATM | |
| SCHEMBL7600868 | 0.94 | FOLH1 (0.45) | FOLH1HTTSLC1A3SLC1A1CTSS | |
| SCHEMBL7597839 | 0.94 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7595812 | 0.94 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7598850 | 0.93 | ALOX5 (0.49) | FOLH1HTTALOX5MAPTL3MBTL1 | |
| SCHEMBL7600469 | 0.92 | TRPM8 (0.46) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL7595116 | 0.92 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7597117 | 0.92 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7601605 | 0.91 | FOLH1 (0.47) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL7595801 | 0.91 | FOLH1 (0.43) | CA1CA2ACHEFOLH1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |