Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600359 | 1.00 | FOLH1 (0.45) | FOLH1MMP1MMP2MMP3MMP7 | |
| SCHEMBL7595812 | 0.94 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7597839 | 0.94 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7595116 | 0.93 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7597117 | 0.93 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7601605 | 0.92 | FOLH1 (0.47) | FOLH1MMP1MMP2MMP3MMP7 | |
| SCHEMBL7600868 | 0.91 | FOLH1 (0.45) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7598850 | 0.90 | ALOX5 (0.49) | FOLH1MMP2MMP9HTT | |
| SCHEMBL7600355 | 0.90 | CA1 (0.45) | FOLH1CNR1CNR2HTTSLC1A3 | |
| SCHEMBL7597929 | 0.90 | CA1 (0.45) | FOLH1CNR1CNR2HTTSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |