Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13032084 | 0.94 | SLC6A9 (0.62) | SLC6A9P2RX7 | |
| SCHEMBL8247219 | 0.87 | SLC6A9 (0.68) | SLC6A9USP2 | |
| SCHEMBL761952 | 0.87 | SLC6A9 (0.68) | SLC6A9USP2 | |
| SCHEMBL5585136 | 0.86 | SLC6A9 (0.81) | SLC6A9P2RX7 | |
| SCHEMBL5584840 | 0.83 | SLC6A9 (0.68) | SLC6A9USP2P2RX7 | |
| SCHEMBL760172 | 0.82 | SLC6A9 (0.54) | SLC6A9 | |
| SCHEMBL5584923 | 0.81 | SLC6A9 (0.66) | SLC6A9USP2P2RX7 | |
| SCHEMBL5584931 | 0.80 | SLC6A9 (0.72) | SLC6A9USP2 | |
| SCHEMBL5585099 | 0.80 | SLC6A9 (0.71) | SLC6A9 | |
| SCHEMBL5584555 | 0.79 | SLC6A9 (0.66) | SLC6A9USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942733-B1 | RADIOLABELED GLYCINE TRANSPORTER INHIBITORS | MERCK SHARP & DOHME (US) | 2012-03-21 | — | — | EP | disclosed |