SCHEMBL7601729

SCHEMBL7601729

Cc1cc(Cn2c(=O)[nH]c(=O)n(Cc3cc(C)c(O)c(C)c3)c2=O)cc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
KDM4E B2RXH2 2/20 0.43
PSMD14 O00487 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
C5AR1 P21730 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CISD1 Q9NZ45 1/20 0.40
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
APEX1 P27695 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 2/20 0.36
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635049 0.89 C5AR1 (0.44) KMT2AMEN1KDM4EC5AR1MAOA
SCHEMBL7631700 0.86 MAOA (0.40) KMT2AMEN1KDM4EPSMD14HPGD
SCHEMBL16200756 0.84 C5AR1 (0.41) KMT2AMEN1KDM4EC5AR1MAOA
SCHEMBL7607371 0.82 ESR1 (0.49) KMT2AMEN1KDM4EPSMD14HPGD
SCHEMBL698535 0.79 ALDH1A1 (0.49) KMT2AMEN1KDM4EHPGDTSHR
SCHEMBL16201609 0.78 ALDH1A1 (0.38) KMT2AMEN1C5AR1MAOAMAOB
SCHEMBL24325204 0.77 TDP1 (0.52) KMT2AMEN1KDM4EHPGDTSHR
SCHEMBL2352374 0.75 CYP1A2 (0.50) KMT2AMEN1KDM4EHPGDTSHR
SCHEMBL7608585 0.75 MAPT (0.45) KMT2AMEN1C5AR1MAPTTHRB
SCHEMBL30552341 0.75 CYP1A2 (0.50) KMT2AMEN1KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6451888-B1 Solid stabilizer composition with improved hydrolytic stability GENERAL ELECTRIC COMPANY 2002-09-17 US disclosed
US-6033600-A PENTAERYTHRITOL PHOSPHITE, A HINDERED PHENOLIC ISOCYANURATE, A METAL SALT OF A FATTY ACID AND HYDROTALCITE. GENERAL ELECTRIC COMPANY (US) 2000-03-07 US disclosed
EP-0685516-B1 Solid stabilizer composition with improved hydrolytic stability GEN ELECTRIC (US) 1999-08-04 EP disclosed
EP-0685516-A1 Solid stabilizer composition with improved hydrolytic stability GENERAL ELECTRIC COMPANY (US) 1995-12-06 EP disclosed
US-5162406-A Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol THE DOW CHEMICAL COMPANY (US) 1992-11-10 US disclosed
US-4923909-A THIXOTROPIC SLURRYING; PIPES; STABILITY; THERMOPLASTIC OR THERMOSETTING RESIN; LIQUID CARRIER THE B. F. GOODRICH COMPANY (US) 1990-05-08 US disclosed
EP-0106169-B1 SUBSTITUTED 2-(2,6-DI-T-BUTYL-4-ALKYLPHENOXY) 4H-1,3,2-BENZODIOXAPHOSPHORINS AND COMPOSITIONS THEREOF The B.F. GOODRICH Company (US) 1988-01-07 EP disclosed
EP-0128368-B1 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES The B.F. GOODRICH Company (US) 1987-08-12 EP disclosed
US-4584146-A Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites THE B. F. GOODRICH COMPANY (US) 1986-04-22 US disclosed
US-4529533-A Substituted 2-(2,6-di-t-butly-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-07-16 US disclosed
US-4501684-A STABILIZERS FOR POLYMERS THE B. F. GOODRICH COMPANY (US) 1985-02-26 US disclosed
US-4495320-A 3,6-Di-t-butyl-2-naphthyl catechol phosphite and compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-01-22 US disclosed
EP-0128368-A1 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes The B.F. GOODRICH Company (US) 1984-12-19 EP disclosed
US-4472548-A HYDROXYPHENYLALKYL ISOCYANURATE, STABILIZERS THE B. F. GOODRICH COMPANY (US) 1984-09-18 US disclosed
EP-0110293-A2 Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof The B.F. GOODRICH Company (US) 1984-06-13 EP disclosed
US-4444929-A Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations THE B. F. GOODRICH COMPANY (US) 1984-04-24 US disclosed
EP-0104643-A2 5-Membered cyclic phosphonates and compositions thereof The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
US-4439564-A 5-Membered cyclic phosphonates and compositions thereof THE B. F. GOODRICH CO. (US) 1984-03-27 US disclosed
US-4415686-A Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof THE B. F. GOODRICH COMPANY (US) 1983-11-15 US disclosed
US-4025486-A PENTAERYTHRITOL PHOSPHITE COMBINATIONS AS ULTRAVIOLET LIGHT STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1977-05-24 US disclosed