Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044520 | 0.91 | LMNA (0.55) | LMNATDP1CYP1A2CA12CA1 | |
| Carbamic Acid SCHEMBL7600209 | 0.85 | PARP10 (0.51) | LMNATDP1CYP1A2SMN1; SMN2PARP10 | |
| SCHEMBL12733864 | 0.84 | LMNA (0.49) | LMNATDP1CYP1A2CA12CA1 | |
| SCHEMBL24762637 | 0.82 | LMNA (0.50) | LMNATDP1CYP1A2CA12CA1 | |
| SCHEMBL9451457 | 0.79 | CA1 (0.56) | LMNATDP1CA12CA1CA2 | |
| SCHEMBL7601766 | 0.77 | LMNA (0.51) | LMNATDP1CA12CA1CA2 | |
| SCHEMBL1281463 | 0.75 | CA12 (0.59) | LMNATDP1CYP1A2CA12CA1 | |
| SCHEMBL614573 | 0.75 | LMNA (0.50) | LMNATDP1CYP1A2SMN1; SMN2PARP10 | |
| SCHEMBL31539875 | 0.75 | LMNA (0.50) | LMNATDP1CYP1A2SMN1; SMN2PARP10 | |
| SCHEMBL3391155 | 0.75 | CA1 (0.47) | LMNATDP1CYP1A2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | claimed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | claimed |