Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599812 | 0.91 | GAA (0.56) | GAAPTGDR2ALDH1A1MTNR1BADRA2C | |
| SCHEMBL7599022 | 0.91 | GAA (0.56) | GAAPTGDR2ALDH1A1MTNR1BADRA2C | |
| SCHEMBL7597944 | 0.83 | GAA (0.47) | GAAPTGDR2ALDH1A1MTNR1BADRA2C | |
| SCHEMBL7601858 | 0.82 | MAPT (0.49) | PTGDR2ALDH1A1CYP2C9 | |
| SCHEMBL7602530 | 0.79 | GAA (0.59) | GAAALDH1A1ADRA2CL3MBTL1POLB | |
| SCHEMBL7600768 | 0.79 | F10 (0.48) | GAAPTGDR2ALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL7597392 | 0.78 | MEN1 (0.45) | GAAALDH1A1L3MBTL1POLBCYP2C9 | |
| SCHEMBL7602651 | 0.76 | GAA (0.52) | GAAPTGDR2ALDH1A1ADRA2CL3MBTL1 | |
| SCHEMBL7601098 | 0.75 | TDP1 (0.48) | PTGDR2ALDH1A1MTNR1BL3MBTL1ATM | |
| SCHEMBL7597396 | 0.75 | PRMT1 (0.64) | GAAALDH1A1POLBATMKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |