Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598284 | 0.89 | GAA (0.50) | GAAADRA2CALDH1A1L3MBTL1POLB | |
| SCHEMBL7599022 | 0.84 | GAA (0.56) | GAAPTGDR2MTNR1BADRA2CALDH1A1 | |
| SCHEMBL7601893 | 0.83 | GAA (0.55) | GAAPTGDR2MTNR1BADRA2CALDH1A1 | |
| SCHEMBL7601098 | 0.82 | TDP1 (0.48) | PTGDR2MTNR1BALDH1A1L3MBTL1ATM | |
| SCHEMBL7600768 | 0.76 | F10 (0.48) | GAAPTGDR2ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL7599801 | 0.75 | CA1 (0.43) | ALDH1A1POLBKDM4ETSHRMAPT | |
| SCHEMBL7601858 | 0.75 | MAPT (0.49) | PTGDR2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7602651 | 0.75 | GAA (0.52) | GAAPTGDR2ADRA2CALDH1A1L3MBTL1 | |
| SCHEMBL7599476 | 0.74 | PTGDR2 (0.46) | GAAPTGDR2MTNR1BADRA2CALDH1A1 | |
| SCHEMBL7599812 | 0.73 | GAA (0.56) | GAAPTGDR2MTNR1BADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |