Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
| ▸ | PYGM | P11217 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601089 | 0.88 | TDP1 (0.51) | TDP1L3MBTL1RAB9APYGLSLC16A1 | |
| SCHEMBL7600768 | 0.83 | F10 (0.48) | TDP1L3MBTL1PYGLPYGMPTGDR2 | |
| SCHEMBL7597944 | 0.82 | GAA (0.47) | TDP1L3MBTL1PTGDR2MEN1KMT2A | |
| SCHEMBL7601858 | 0.82 | MAPT (0.49) | PYGLPYGMPTGDR2MEN1KMT2A | |
| SCHEMBL7598984 | 0.78 | MAPT (0.51) | MEN1KMT2ARXFP1MAPTALDH1A1 | |
| SCHEMBL7599476 | 0.76 | PTGDR2 (0.46) | TDP1L3MBTL1PYGMPTGDR2MAPT | |
| SCHEMBL7599022 | 0.76 | GAA (0.56) | TDP1L3MBTL1PTGDR2MEN1KMT2A | |
| SCHEMBL7601893 | 0.75 | GAA (0.55) | L3MBTL1PTGDR2ALDH1A1ATMMTNR1B | |
| SCHEMBL7601959 | 0.74 | PYGM (0.37) | TDP1L3MBTL1RAB9APYGLPYGM | |
| SCHEMBL7601939 | 0.74 | TDP1 (0.38) | TDP1L3MBTL1RAB9APYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |