Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | MITF | O75030 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | CDC25A | P30304 | 3/20 | 0.53 |
| ▸ | CDC25B | P30305 | 3/20 | 0.53 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602280 | 0.80 | MAPT (0.51) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL7600243 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1MITFNPSR1SMN1; SMN2 | |
| SCHEMBL7602213 | 0.79 | AURKA (0.46) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL7599289 | 0.77 | ALDH1A1 (0.51) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL571557 | 0.72 | MAPT (1.00) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL29545010 | 0.72 | MAPT (1.00) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL9628178 | 0.72 | MAPT (1.00) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL29079807 | 0.70 | APP (0.46) | ALDH1A1SMN1; SMN2TP53HPGDKMT2A | |
| SCHEMBL20100968 | 0.69 | MAPT (0.62) | MAPTALDH1A1MITFHTTNPSR1 | |
| SCHEMBL7599738 | 0.69 | BACE1 (0.51) | MAPTALDH1A1HTTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |