SCHEMBL29545010

SCHEMBL29545010

COC1=C(OC)C(=O)c2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 1.00
ALDH1A1 P00352 8/20 1.00
POLB P06746 8/20 1.00
KDM4E B2RXH2 7/20 1.00
SMN1; SMN2 Q16637 7/20 1.00
LMNA P02545 6/20 1.00
RAB9A P51151 6/20 1.00
HPGD P15428 5/20 1.00
CDC25B P30305 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
CDC25A P30304 3/20 1.00
BLM P54132 2/20 1.00
MAP2K7 O14733 1/20 1.00
GMNN O75496 1/20 1.00
TP53 P04637 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
ALOX15 P16050 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571557 1.00 MAPT (1.00) MAPTALDH1A1POLBKDM4ESMN1; SMN2
Benzoquinone SCHEMBL6130614 0.91 MAPT (0.82) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL30002742 0.87 CDC25B (1.00) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL3414838 0.87 CDC25B (1.00) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL16138414 0.87 MAPT (0.75) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL10901421 0.87 MAPT (0.75) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL8285443 0.84 MAPT (0.71) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL9562528 0.84 MAPT (0.71) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL1436501 0.84 MAPT (0.71) MAPTALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL14662804 0.84 MAPT (0.71) MAPTALDH1A1POLBKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119606931-A Application of 2, 3-dimethoxy-1, 4-naphthoquinone in preparation of inducer for inducing death of tumor cell iron and medicine for treating gastric cancer 济南市中心医院 2025-03-14 CN claimed
WO-2023246464-A1 USE OF CRYPTOTANSHINONE SUBSTANCE AND COMBINED COMPOSITION THEREOF 澳门大学 2023-12-28 WO claimed
EP-4218819-A2 COMBINATION THERAPY BASED ON PD-1 SIGNAL INHIBITORS Kyoto University (JP) 2023-08-02 EP claimed
WO-2023068423-A1 COMPLEX ANTICANCER DRUG COMPOSITION USING PHOTOREACTIVITY AND PREPARATION METHOD THEREFOR 닥터아이앤비(주) 2023-04-27 WO claimed
CN-115054608-A Application of cryptotanshinone substances and combination composition thereof 澳门大学 2022-09-16 CN claimed
CN-114601930-A Combination therapy of PD-1 signaling inhibitors 国立大学法人京都大学 2022-06-10 CN claimed
CN-114404595-A Combination therapy of PD-1 signaling inhibitors 国立大学法人京都大学 2022-04-29 CN claimed
US-20260083701-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR TREATMENT OF INFLAMMATORY CONDITIONS ODDITY LABS LLC (US) 2026-03-26 US disclosed
EP-4688151-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR TREATMENT OF INFLAMMATORY CONDITIONS Oddity Labs, LLC (US) 2026-02-11 EP disclosed
EP-4635959-A1 NOVEL CRYSTALLINE FORM OF MAGNESIUM-SERINATE AND METHOD FOR PRODUCING SAME Astrogen, Inc. (KR) 2025-10-22 EP disclosed
US-20250288542-A1 METHODS AND COMPOSITIONS TO TREAT AND PREVENT VIRAL INFECTIONS AND ACUTE RESPIRATORY DISTRESS SYNDROME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-18 US disclosed
WO-2025110267-A1 L-SERINE HAVING REDUCED HEAVY METAL CONTENT, PHARMACEUTICAL COMPOSITION THEREOF, METHOD FOR PREPARING SAME, AND USE THEREOF 주식회사 아스트로젠 2025-05-30 WO disclosed
WO-2025110614-A1 L-SERINE HAVING REDUCED HEAVY METAL AMOUNT, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF 주식회사 아스트로젠 2025-05-30 WO disclosed
US-20220362260-A1 METHODS OF TREATING LIPEDEMA INCLUDING AKR1C1 AS A THERAPEUTIC TARGET MAGI EUREGIO SCS (IT) 2022-11-17 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
CN-115054608-A Application of cryptotanshinone substances and combination composition thereof 澳门大学 2022-09-16 CN disclosed
EP-2858974-B9 LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORP (JP) 2022-07-20 EP disclosed
CN-114601930-A Combination therapy of PD-1 signaling inhibitors 国立大学法人京都大学 2022-06-10 CN disclosed
CN-114404595-A Combination therapy of PD-1 signaling inhibitors 国立大学法人京都大学 2022-04-29 CN disclosed
WO-2022072745-A1 METHODS AND COMPOSITIONS TO TREAT AND PREVENT VIRAL INFECTIONS AND ACUTE RESPIRATORY DISTRESS SYNDROME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083701-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR TREATMENT OF INFLAMMATORY CONDITIONS IL23R, NR3C2, HCRTR2 MAPT 3377/4885ALDH1A1 2818/4885POLB 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.