Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MMP3 | P08254 | 8/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598954 | 0.91 | HSD17B10 (0.54) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7598458 | 0.89 | HSD17B10 (0.42) | HSD17B10MMP3MMP1 | |
| SCHEMBL7598874 | 0.86 | HSD17B10 (0.62) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7605750 | 0.86 | HSD17B10 (0.56) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7599480 | 0.85 | HSD17B10 (0.61) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7597454 | 0.84 | HSD17B10 (0.47) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7602546 | 0.84 | HSD17B10 (0.59) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7597343 | 0.82 | HSD17B10 (0.54) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7603452 | 0.80 | HSD17B10 (0.55) | HSD17B10MMP3MMP1ACE2 | |
| SCHEMBL7602114 | 0.80 | CTSV (0.40) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |
| US-5716943-A | CARDIOVASCULAR DISORDERS | ZAMBON GROUP. S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |