Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602114 | 0.90 | CTSV (0.40) | HSD17B10NAMPT | |
| SCHEMBL7599751 | 0.90 | HSD17B10 (0.47) | HSD17B10MMP1MMP3MMP2 | |
| SCHEMBL7602207 | 0.89 | HSD17B10 (0.58) | HSD17B10MMP1MMP3 | |
| SCHEMBL7607450 | 0.85 | HSD17B10 (0.40) | HSD17B10SMN1; SMN2NPC1RAB9AMMP1 | |
| SCHEMBL8641490 | 0.85 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2NPC1RAB9AMMP1 | |
| SCHEMBL7601877 | 0.84 | HSD17B10 (0.44) | HSD17B10NPC1RAB9AMMP1MMP3 | |
| SCHEMBL7598806 | 0.82 | HSD17B10 (0.43) | HSD17B10MMP1MMP3MMP2 | |
| SCHEMBL7598837 | 0.81 | HSD17B10 (0.39) | HSD17B10MMP1MMP3MMP2 | |
| SCHEMBL7598954 | 0.80 | HSD17B10 (0.54) | HSD17B10MMP1MMP3 | |
| SCHEMBL7598935 | 0.79 | HSD17B10 (0.40) | HSD17B10MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |
| US-5716943-A | CARDIOVASCULAR DISORDERS | ZAMBON GROUP. S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |