Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931928 | 0.86 | ALDH1A1 (0.56) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL4666382 | 0.85 | POLB (0.76) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL8266826 | 0.85 | POLB (0.76) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL23249644 | 0.83 | ALDH1A1 (0.55) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL7829243 | 0.83 | NPC1 (0.48) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL26428319 | 0.82 | HTR2A (0.60) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL23762398 | 0.82 | HTR2A (0.60) | MAPTKDM4EL3MBTL1APAF1POLB | |
| SCHEMBL9773066 | 0.80 | HTR2A (0.71) | MAPTKDM4EALDH1A1CYP1A2MEN1 | |
| SCHEMBL29611875 | 0.80 | HTR2A (0.71) | MAPTKDM4EALDH1A1CYP1A2MEN1 | |
| SCHEMBL1250035 | 0.80 | HTR2A (0.71) | MAPTKDM4EALDH1A1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254114-A2 | MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | Melacure Therapeutics AB (SE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055106-A2 | NOVEL MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |