Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602497 | 0.83 | MAPT (0.59) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL28931928 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL1769610 | 0.78 | MAPT (0.74) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL1769607 | 0.78 | MAPT (0.74) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL29414366 | 0.78 | MAPT (0.74) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL27426182 | 0.78 | MAPT (0.74) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL5738746 | 0.78 | CYP3A4 (0.65) | ALDH1A1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1233175 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL664283 | 0.77 | MAPT (0.70) | ALDH1A1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL7969785 | 0.77 | HTR2A (0.62) | ALDH1A1MAPTGAACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045043-A1 | COMPOUNDS AND METHODS FOR MODULATING IMMUNE-RELATED PROTEINS | Vividion Therapeutics, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |
| WO-2021076703-A1 | COMPOUNDS AND METHODS FOR MODULATING IMMUNE-RELATED PROTEINS | VIVIDION THERAPEUTICS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |