Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719602 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAARAB9A | |
| SCHEMBL7596986 | 0.81 | BACE1 (0.53) | BACE1PTPN1CASP3ALDH1A1KDM4E | |
| SCHEMBL7598965 | 0.80 | BACE1 (0.48) | BACE1PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL7600057 | 0.77 | BACE1 (0.42) | BACE1PTPN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7599782 | 0.77 | SOAT1 (0.46) | BACE1PTPN1ALDH1A1GAARAB9A | |
| SCHEMBL7598566 | 0.76 | SOAT1 (0.47) | BACE1PTPN1ALDH1A1GAARAB9A | |
| SCHEMBL7597649 | 0.76 | SOAT1 (0.47) | BACE1PTPN1ALDH1A1GAARAB9A | |
| SCHEMBL7599738 | 0.74 | BACE1 (0.51) | BACE1PTPN1CASP3ALDH1A1GAA | |
| SCHEMBL28336955 | 0.74 | SIRT2 (0.55) | BACE1ALDH1A1SMN1; SMN2TDP1PTPRC | |
| SCHEMBL7601683 | 0.73 | MAPK1 (0.45) | BACE1PTPN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | claimed |
| EP-0861830-A1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | L'OREAL (FR) | 1998-09-02 | — | — | EP | claimed |
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | disclosed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |
| EP-0861830-A1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | L'OREAL (FR) | 1998-09-02 | — | — | EP | disclosed |