Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602586 | 0.81 | BACE1 (0.49) | BACE1PTPN1CASP3NTRK1CDC25B | |
| SCHEMBL7600067 | 0.75 | BACE1 (0.56) | BACE1PTPN1CASP3CDC25BPTPRC | |
| SCHEMBL7596925 | 0.75 | SOAT1 (0.49) | BACE1PTPN1ALDH1A1ALDH2CES1 | |
| SCHEMBL7597937 | 0.74 | SOAT1 (0.50) | BACE1PTPN1ALDH1A1ALDH2CES1 | |
| SCHEMBL7601133 | 0.74 | SOAT1 (0.50) | BACE1PTPN1ALDH1A1ALDH2CES1 | |
| SCHEMBL6555840 | 0.73 | BACE1 (0.75) | BACE1PTPN1CDC25BPTPRCPTPRF | |
| SCHEMBL7603723 | 0.73 | BACE1 (0.46) | BACE1PTPN1CDC25BPTPRCALDH1A1 | |
| SCHEMBL28336955 | 0.72 | SIRT2 (0.55) | BACE1PTPRCALDH1A1KMT2AMEN1 | |
| SCHEMBL29673492 | 0.70 | BACE1 (1.00) | BACE1PTPN1CDC25BPTPRCPTPRF | |
| SCHEMBL5485068 | 0.70 | BACE1 (1.00) | BACE1PTPN1CDC25BPTPRCPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | claimed |
| EP-0861830-A1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | L'OREAL (FR) | 1998-09-02 | — | — | EP | claimed |
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | disclosed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |
| EP-0861830-A1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | L'OREAL (FR) | 1998-09-02 | — | — | EP | disclosed |