SCHEMBL7602705

SCHEMBL7602705

Cc1cc(C(F)(C(F)F)C(F)(F)F)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.35
MCL1 Q07820 5/20 0.33
AR P10275 2/20 0.33
TSHR P16473 2/20 0.32
HSD11B1 P28845 4/20 0.32
S1PR1 P21453 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4004120 0.82 ALDH1A1 (0.33)
SCHEMBL7606344 0.79 CYP3A4 (0.38) RAPGEF4
SCHEMBL4200965 0.78 CYP3A4 (0.42) PDE2AARTSHRSMN1; SMN2
SCHEMBL7458360 0.78 CHRNA1 (0.33)
SCHEMBL23174685 0.78 ESR1 (0.52) AR
SCHEMBL7603610 0.77 HRH4 (0.32) PDE2AAR
SCHEMBL28844796 0.76 CYP3A4 (0.41) PDE2AARTSHR
SCHEMBL28445611 0.76 TSHR (0.41) PDE2AARTSHRKMT2A
SCHEMBL9578158 0.76 ALDH1A1 (0.41) PDE2AARTSHRKMT2ASMN1; SMN2
SCHEMBL3956006 0.76 ESR1 (0.41) PDE2AMCL1ARTSHRS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020064953-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2002-05-30 US disclosed