SCHEMBL7606344

SCHEMBL7606344

Cc1cc(C(F)(C(F)F)C(F)(F)F)cc(C)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
CHRM1 P11229 1/20 0.38
ALOX15 P16050 1/20 0.38
MAOA P21397 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043799 0.79 ESR1 (0.42) CYP3A4
SCHEMBL7461094 0.79
SCHEMBL7602705 0.79 PDE2A (0.35) RAPGEF4
SCHEMBL28065977 0.78 PGK1 (0.36)
SCHEMBL4004120 0.75 ALDH1A1 (0.33)
SCHEMBL3947356 0.73 CYP3A4 (0.44) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL5360962 0.73 CYP3A4 (0.44) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL1755264 0.72 RAPGEF4 (0.48) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL21727424 0.71
SCHEMBL23174685 0.71 ESR1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020064953-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2002-05-30 US disclosed