SCHEMBL7602794

SCHEMBL7602794

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](C)(C)CC[Zr](C)(C)C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP2A6 P11509 1/20 0.32
SLC6A4 P31645 3/20 0.31
DHFR P00374 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A3 Q01959 2/20 0.31
CYP2D6 P10635 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
TDP2 O95551 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28266415 0.87 ALDH1A1 (0.34) CA12CA1CA2CA9ALDH1A1
SCHEMBL7639241 0.86 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL7599308 0.84 CNR2 (0.32) SLC6A4SLC6A2SLC6A3CYP2D6CNR2
Hydrochloric Acid SCHEMBL7629330 0.84 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL2525070 0.83 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL7640575 0.83 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
Propane SCHEMBL8630893 0.83 SLC6A4 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL7601460 0.83 CA12 (0.32) CA12CA1CA2CA9ALDH1A1
Ethane SCHEMBL8631691 0.83 ALDH1A1 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL7604235 0.82 PDCD1 (0.35) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed